The Bernstein Center for Computational Neuroscience Göttingen invites
applications for a PhD student position (BATIIa/2) in cellular
neuroscience.
The successful candidate will use biophysical methods to characterize
the synaptic mechanisms that mediate the coding of sound intensity
and timing by the first synapse in the auditory pathway. Recently, we
found evidence that at the active zone of the inner hair cell the
exocytosis of a given synaptic vesicle may be controlled by only one
or few nearby Ca2+ channel(s). This Ca2+ nanodomain control of
transmitter release implies that sound coding is determined by the
stochastic gating of single Ca2+ channels. The successful candidate
will study the relationship of Ca2+ channel opening and single
vesicle exocytosis at the microscopic, single active zone level. This
will be done by cell-attached patch-clamp recordings from inner hair
cells and accompanying modelling of the synaptic signalling cascade.
We are looking for applicants with a first degree in a natural
science, preferably with prior experience in biophysics and
neuroscience.
The candidate's PhD research will be supported the recently
established Bernstein Center for Computational Neuroscience (BCCN) in
Göttingen. Göttingen is a center of neuroscience in Europe hosting
numerous internationally recognized neuroscience research
institutions, including three Max Planck Institutes, the European
Neuroscience Institute, the German Primate Research Center, and
Göttingen University's Centers for Systems Neuroscience (ZNV) and for
the Molecular Physiology of the Brain (CMPB). The BCCN integrates
theoretical and experimental research groups from these institutions
to foster interdisciplinary research in computational neuroscience
specifically supporting close collaboration between theorists and
experimental researchers.
Please submit your application preferably in one single PDF-document,
including cover letter, CV, list of publications, names of possible
referees, relevant certificates to: jobs [ à ] bccn-goettingen.de (Subject:
BioPhAN PhD)
While e-mail is preferred, applications may also be submitted in
hardcopy to the following address:
Dr. Andreas Neef
Subject: BioPhAN PhD
InnerEarLab
Department of Otolaryngology
University Clinics Goettingen
D-37099 Goettingen
Germany
http://www.bccn-goettingen.deThe BCCN is an equal opportunity employer.